Which is which?
Business or Non-Profit.
These are clients who own for-profit businesses, registered non-profit organisations, or are representatives of businesses or non-profits. These clients use mass media to bring attention to a product, service, or cause. This also applies to clients whose projects have commercial sponsorship, including but not limited to YouTube channels, livestreams, and podcasts.
Independent Creators.
These are people with non-commercial endeavours, such as Twitch streams, and YouTube channels. While they might make a little money doing it, their project is not owned by a large company, corporation, or non-profit organisation.
While attempting to concretely separate these into absolutely discrete categories is difficult, I can make a generalisation. If the entity whose project you want me to work on supplies you with enough money that you can consider it your main source of income, you're a Business. If the entity whose project you want me to work on is registered with the state government as a 501(c)(3) or 501(c)(7), you're a Non-Profit. If your project is yours alone, you're an independent creator.
Still confused? So am I. Here's an example...
If your YouTube channel has supporters on Patreon, click here.
If your YouTube channel is sponsored by Patreon itself, click here.
If you set up your YouTube channel as part of your job at Patreon Inc., click here.